Hydrogen sulfide has recently been described as a third gaseous signalling molecule which has been implicated in a numerous biologcal pathways. We have developed a H2S sensing azido pyrene molecule based on the fluorescent dye aminopyrene trisulfonic acid. In the absence of hydrogen sulfide, the molecule is non-fluorescent, but upon treatment with H2S, the molecule becomes highly fluorescent. The azidopyrene molecule reacts selectively with hydrogen sulfide vs other biologically relevent thiols like cysteine and glutathione. The dye is also highly water soluble and can measure hydrogen sulfide levels in highly complicated biological fluids, like serum. To learn more click here.